Gene Expression Profile Of Lncrna Meg3 In Prostate Cancer And Normal Cell Lines

Background and Aim: Cancer is one of the major human problems prostate cancer a popular healthy problem in cancers. In spite developing treatment methods, cannot be treated effectively.Therefore, identification novel genes that will role diagnosis greatest interestmeg3 (meg3 family tumer suprosser gene are key regulators programed death cell . Objective Although studies have saw this meg 3 has processes, its usefulness not been fully elucidated.At same time, previous shown 3gene associated with important protein apoptosis triggering proteins such as HAGLR TSIX. study, by using expression level, we aimed to investigate relationship between levels meg3,and haglrgene which prognosis processes line. Materials Methods: Collected sample from normal tissue type line, RNA isolated cell, quantitation, cDNA synthesised, quantitation ,and Real -time PCR was performed see level two types genes. Results: meg3 supresur significantly lessened regulator molecule tissues line contrast HAGLRprotein, no significant difference detected TSIX level. However, Our study also showed low clinic characteristics patient tumor grade, stage breast type. Conclusion: Findings our show roles formation might biomarker for cancer.